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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Mm. Psen1, presenilin 1
Sequence ID:NM_008943
Entrez Gene ID:19164
Ensembl ID:ENSMUSG00000019969

Database Links

UniGeneEntrez GeneEnsembl GeneSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, limb, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12 D1|12 37.0 cM

Chromosomal Position (from UCSC)

Chromosomal Position:12: 83699564 - 83734071

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3673609Full LengthBC071233presenilin 1
4511140Full LengthBC014744presenilin 1
5133302Full LengthBC030409presenilin 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_032969  

Protein Infomation

NM_008943 NP_032969 Q3UYK2

Related Sequences

L42177 AAC42094 Q3UYK2
AF149111 AAF73153 P49769
BC014744 AAH14744 P49769
BC030409 AAH30409 Q3UYK2
BC071233 AAH71233 Q3UYK2
AK134232 BAE22058 Q3UYK2
AK134615 BAE22210 Q3UYK2
AK148101 BAE28344 Q3UYK2
AK165984 BAE38500 Q3UYK2
AK169963 BAE41486 Q3TDW2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
M.musculus Psen1 NP_032969 R.norvegicus Psen1 29192   NP_062036 97
H.sapiens PSEN1 5663 Gene Info NP_000012 93
A.gambiae AgaP_AGAP002957 1273006   XP_311942 66
D.melanogaster Psn 40260   NP_001137988 59
C.elegans sel-12 180441   NP_508175 57
A.thaliana PS1 837391   NP_172346 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta