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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Mthfr, 5,10-methylenetetrahydrofolate reductase
Sequence ID:NM_001161798
NM_010840
NR_027809
Entrez Gene ID:17769
Ensembl ID:ENSMUSG00000029009

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:4 E2|4 76.4 cM

Chromosomal Position (from UCSC)

Chromosomal Position:4: 148038316 - 148041642

 Exon Info From UCSC:
NM_001161798
NM_010840

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6308248Full LengthBC0510175,10-methylenetetrahydrofolate reductase
6834886Full LengthBC0524665,10-methylenetetrahydrofolate reductase
5698272IncompleteBC1005505,10-methylenetetrahydrofolate reductase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_034970  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001161798 NP_001155270      
NM_010840 NP_034970 Q9WU20 EC 1.5.1.20 MTHFR

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC051017 AAH51017 Q9WU20 EC 1.5.1.20
BC052466 AAH52466 Q9WU20 EC 1.5.1.20
BC100550 AAI00551 Q497H7  
AF404270 AAN40872 Q8CJA9  
AF404271 AAN40873 Q8CJA8  
AF404272 AAN40874 Q8CJA7  
AF404273 AAN40875 Q8CJA6  
AF404274 AAN40876 Q8CJA5  
AK030192 BAC26832 Q9WU20 EC 1.5.1.20
AK150159 BAE29349 Q3UDB2  
AK043144 BAE43318 Q3V399  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Mthfr NP_001155270 R.norvegicus Mthfr 362657   XP_342976 96
H.sapiens MTHFR 4524 Gene Info NP_005948 91
C.elegans C06A8.1 174254   NP_741028 50
N.crassa NCU07690 3877877   XP_961729 48
A.thaliana MTHFR2 819022   NP_566011 45
A.thaliana MTHFR1 825167   NP_191556 45
S.pombe met9 2542993   NP_593224 44
S.cerevisiae MET13 852752   NP_011390 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)