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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Gclc, glutamate-cysteine ligase, catalytic subunit
Sequence ID:NM_010295
Entrez Gene ID:14629
Ensembl ID:ENSMUSG00000032350

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:9 D-E|9 42.0 cM

Chromosomal Position (from UCSC)

Chromosomal Position:9: 77754531 - 77756279

 Exon Info From UCSC:
NM_010295

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4195425Full LengthBC019374glutamate-cysteine ligase, catalytic subunit

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_034425  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_010295 NP_034425 P97494
Q3TEF1
EC 6.3.2.2 GCS

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U85414 AAB42020 P97494 EC 6.3.2.2
U85498 AAB52542 P97494
Q3TEF1
EC 6.3.2.2
BC019374 AAH19374 P97494 EC 6.3.2.2
AK144339 BAE25840 Q3UNA7  
AK160876 BAE36064 P97494
Q3TEF1
EC 6.3.2.2
AK169676 BAE41297 P97494
Q3TEF1
EC 6.3.2.2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Gclc NP_034425 R.norvegicus Gclc 25283   NP_036947 98
H.sapiens GCLC 2729 Gene Info NP_001489 95
A.gambiae AgaP_AGAP001512 1281664   XP_321610 64
D.melanogaster Gclc 53581   NP_525005 59
C.elegans gcs-1 174438   NP_495927 56
S.pombe gcs1 2541881   NP_593031 53
N.crassa NCU01157 3877703   XP_961523 51
S.cerevisiae GSH1 853344   NP_012434 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)