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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Mm. Hmgcs1, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
Sequence ID:NM_145942
Entrez Gene ID:208715
Ensembl ID:ENSMUSG00000093930

Database Links

UniGeneEntrez GeneEnsembl GeneSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, bone marrow, brain, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, limb, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, retina, skin, spleen, stem cell, synovium, t-cell, testis, thymus, uncharacterized tissue
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:13 66.0 cM|13

Chromosomal Position (from UCSC)

Chromosomal Position:13: 119690463 - 119708260

 Exon Info From UCSC:
NM_145942

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5347038Full LengthBC0238513-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
5357048Full LengthBC0313633-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
5366786Full LengthBC0343173-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
5375374Full LengthBC0296933-hydroxy-3-methylglutaryl-Coenzyme A synthase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_666054  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_145942 NP_666054 Q8JZK9 EC 2.3.3.10 HMG_CoA_synt_N
HMG_CoA_synt_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC023851 AAH23851 Q8JZK9 EC 2.3.3.10
BC029693 AAH29693 Q8JZK9 EC 2.3.3.10
BC031363 AAH31363 Q8K0I5  
BC034317 AAH34317 Q8JZK9 EC 2.3.3.10
AK031297 BAC27338 Q8JZK9 EC 2.3.3.10
AK044835 BAC32112 Q8JZK9 EC 2.3.3.10
AK045094 BAC32218 Q8JZK9 EC 2.3.3.10
AK078743 BAC37373 Q8C5F4  
AK135551 BAE22579 Q8JZK9 EC 2.3.3.10
AK136171 BAE22855 Q3UWQ9  
AK146042 BAE26854 Q3UKE7  
AK146351 BAE27103 Q3UJQ2  
AK146590 BAE27285 Q3UJ70  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Hmgcs1 NP_666054 M.musculus LOC100040592 100040592   XP_001475239 100
R.norvegicus Hmgcs1 29637   NP_058964 98
H.sapiens HMGCS1 3157 Gene Info NP_002121 95
A.gambiae AgaP_AGAP005847 1276514   XP_315872 65
D.melanogaster Hmgs 44154   NP_725567 65
N.crassa NCU03922 3873746   XP_957561 52
S.cerevisiae ERG13 854913   NP_013580 51
A.thaliana MVA1 826788   NP_192919 50
S.pombe hcs1 2543141   NP_593859 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta