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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Mm. Smpd1, sphingomyelin phosphodiesterase 1, acid lysosomal
Sequence ID:NM_011421
Entrez Gene ID:20597
Ensembl ID:ENSMUSG00000037049

Database Links

UniGeneEntrez GeneEnsembl GeneSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, limb, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, vascular
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7 E3|7 51.0 cM

Chromosomal Position (from UCSC)

Chromosomal Position:7: 105554391 - 105558383

NM_011421 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1478112702873112703350
4791251112703735112704507
12521423112705020112705191
14241500112705431112705507
15011646112705863112706008
16472411112706137112706901

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3964394Full LengthBC011304sphingomyelin phosphodiesterase 1, acid lysosomal
4482098Full LengthBC034515sphingomyelin phosphodiesterase 1, acid lysosomal

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_035551  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_011421 NP_035551 Q04519 EC 3.1.4.12 Metallophos

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC011304 AAH11304 Q04519 EC 3.1.4.12
BC034515 AAH34515 Q8K011  
AK088147 BAC40171 Q04519 EC 3.1.4.12
AK145534 BAE26489 Q04519 EC 3.1.4.12
AK145702 BAE26598 Q04519 EC 3.1.4.12
AK148189 BAE28406 Q3UG03  
AK149579 BAE28971 Q3UEE0  
AK164167 BAE37659 Q04519 EC 3.1.4.12
Z14252 CAA78619 Q04519 EC 3.1.4.12

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Smpd1 NP_035551 R.norvegicus Smpd1 308909   NP_001006998 96
H.sapiens SMPD1 6609 Gene Info NP_001007594 83
A.gambiae AgaP_AGAP011940 1280729   XP_320591 44
D.melanogaster CG3376 37884   NP_726435 43
C.elegans asm-2 181323   NP_509894 39
C.elegans asm-3 176879   NP_001040996 38
C.elegans asm-1 174131   NP_495415 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta