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Gene Info

Gene Information For:Mm. Mthfd2, methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
Sequence ID:NM_008638
Entrez Gene ID:17768
Ensembl ID:ENSMUSG00000005667

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebrum, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, vascular
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:6 C3|6 35.15 cM

Chromosomal Position (from UCSC)

Chromosomal Position:6: 83305985 - 83317556

NM_008638 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
111068325569783256802
110712328325892683259051
123313258325945583259547
132614338326040583260512
143415868326120383261355
158717098326180583261927
171018948326335583263539
189520708326742283267597

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4164253Full LengthBC019511methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_032664  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_008638 NP_032664 P18155 EC 3.5.4.9
EC 1.5.1.15
THF_DHG_CYH
THF_DHG_CYH_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
J04627 AAA39827 P18155 EC 3.5.4.9
EC 1.5.1.15
BC019511 AAH19511 P18155 EC 3.5.4.9
EC 1.5.1.15
AK076019 BAC36124 P18155 EC 3.5.4.9
EC 1.5.1.15
AK152249 BAE31071 Q3U8E7  
AK159680 BAE35283 P18155 EC 3.5.4.9
EC 1.5.1.15
AK165840 BAE38407 P18155 EC 3.5.4.9
EC 1.5.1.15

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Mthfd2 NP_032664 R.norvegicus Mthfd2 680308   NP_001102868 97
H.sapiens MTHFD2 10797 Gene Info NP_006627 92
A.gambiae AgaP_AGAP004677 1275382   XP_001687783 62
D.melanogaster Nmdmc 47895   NP_476929 56

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)