Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Sirt1, Sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)
Sequence ID:NM_019812
NM_001159589
Entrez Gene ID:93759
Ensembl ID:ENSMUSG00000020063

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:10 B4|10

Chromosomal Position (from UCSC)

Chromosomal Position:10: 63319060 - 63339017

 Exon Info From UCSC:
NM_019812
NM_001159589

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40111573Full LengthBC152314sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)
100066295Full LengthBC165995sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)
3587177IncompleteBC006584sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_062786  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001159589 NP_001153061    
NM_019812 NP_062786 Q923E4
Q53Z05
SIR2

Related Sequences

 
mRNAGenPeptSwissProt
AF214646 AAF24983 Q923E4
Q53Z05
BC006584 AAH06584 Q923E4
BC152314 AAI52315 A7MCT8
BC165995 AAI65995  
AY377984 AAR23928 Q923E4
Q53Z05
AK139946 BAE24193 Q3USY7
AK140330 BAE24339 Q3USJ2
AK144203 BAE25766 Q3UNI1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Sirt1 NP_062786 H.sapiens SIRT1 23411 Gene Info NP_036370 88
C.elegans sir-2.1 177924   NP_501912 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta