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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Hmgcr, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Sequence ID:NM_008255
Entrez Gene ID:15357
Ensembl ID:ENSMUSG00000021670

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebellum, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, testis, thymus, uncharacterized tissue, vascular
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:13 D1|13 49.0 cM

Chromosomal Position (from UCSC)

Chromosomal Position:13: 96661121 - 96663822

 Exon Info From UCSC:
NM_008255

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5320486Full LengthBC0850833-hydroxy-3-methylglutaryl-Coenzyme A reductase
6810312IncompleteBC0598733-hydroxy-3-methylglutaryl-Coenzyme A reductase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_032281  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_008255 NP_032281 Q01237 EC 1.1.1.34 HMG-CoA_red

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M62766 AAA37819 Q01237 EC 1.1.1.34
BC059873 AAH59873 Q6PB59  
BC085083 AAH85083 Q01237 EC 1.1.1.34
AK079302 BAC37602 Q8BV96  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Hmgcr NP_032281 R.norvegicus Hmgcr 25675   NP_037266 97
H.sapiens HMGCR 3156 Gene Info NP_000850 94
N.crassa NCU00712 3880697   XP_964546 61
S.cerevisiae HMG2 851171   NP_013555 59
A.thaliana HMG1 843982   NP_177775 58
S.pombe hmg1 2538999   NP_588235 56
D.melanogaster Hmgcr 42803   NP_001163703 51
A.gambiae AgaP_AGAP002288 1269263   XP_307890 51
C.elegans F08F8.2 176047   NP_498626 50
S.cerevisiae HMG1 854900   NP_013636 45

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)