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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Mm. Mdh2, malate dehydrogenase 2, NAD (mitochondrial)
Sequence ID:NM_008617
Entrez Gene ID:17448
Ensembl ID:ENSMUSG00000019179

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5 G2|5 78.0 cM

Chromosomal Position (from UCSC)

Chromosomal Position:5: 135778631 - 135790387

NM_008617 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1153136254518136254670
154322136259174136259342
323406136260053136260136
407516136261798136261907
517642136262102136262227
643720136263410136263487
721820136265070136265169
821972136265495136265646
9731282136265946136266255

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5251192Full LengthBC023482malate dehydrogenase 2, NAD (mitochondrial)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_032643  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_008617 NP_032643 P08249 EC 1.1.1.37 Ldh_1_N
Ldh_1_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M16229 AAA39509 P08249 EC 1.1.1.37
BC023482 AAH23482 P08249 EC 1.1.1.37
DQ402950 ABD77283 P08249 EC 1.1.1.37
AK002305 BAC24986 P08249 EC 1.1.1.37
AK135162 BAE22447 P08249 EC 1.1.1.37
AK160553 BAE35869 P08249 EC 1.1.1.37
AK167809 BAE39836 P08249 EC 1.1.1.37

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Mdh2 NP_032643 R.norvegicus Mdh2 81829   NP_112413 99
H.sapiens MDH2 4191 Gene Info NP_005909 95
A.gambiae AgaP_AGAP001903 1281223   XP_321163 66
D.melanogaster CG7998 42185   NP_650696 62
A.thaliana mMDH2 820731   NP_188120 58
A.thaliana mMDH1 841757   NP_564625 58
C.elegans mdh-1 175936   NP_498457 57
N.crassa NCU04899 3874555   XP_958408 57
S.cerevisiae MDH1 853777   NP_012838 54
S.pombe SPCC306.08c 2538766   NP_587816 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)