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Gene Info

Gene Information For:Mm. Mthfd1, methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
Sequence ID:NM_138745
Entrez Gene ID:108156
Ensembl ID:ENSMUSG00000021048

Database Links

UniGeneEntrez GeneEnsembl GeneSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pituitary gland, placenta, pooled tissue, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue, vascular
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12 D2|12

Chromosomal Position (from UCSC)

Chromosomal Position:12: 76255450 - 76317700

 Exon Info From UCSC:
NM_138745

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3590449Full LengthBC008523methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
3590876IncompleteBC013563methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_620084  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_138745 NP_620084 Q922D8 EC 1.5.1.5
EC 6.3.4.3
EC 3.5.4.9
THF_DHG_CYH
FTHFS
THF_DHG_CYH_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC008523 AAH08523 Q922D8 EC 1.5.1.5
EC 6.3.4.3
EC 3.5.4.9
AF364579 AAL99692 Q922D8 EC 1.5.1.5
EC 6.3.4.3
EC 3.5.4.9
AK042019 BAC31133 Q8BY49  
AK042958 BAC31419 Q8BXX7  
AK088700 BAC40513 Q922D8 EC 1.5.1.5
EC 6.3.4.3
EC 3.5.4.9
AK133848 BAE21884 Q3UZH3  
AK159812 BAE35392 Q3TW74  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Mthfd1 NP_620084 R.norvegicus Mthfd1 64300   NP_071953 97
H.sapiens MTHFD1 4522 Gene Info NP_005947 93
C.elegans K07E3.4 181064   NP_509361 71
A.thaliana THFS 841470   NP_564571 68
A.gambiae AgaP_AGAP002830 1273131   XP_312083 64
D.melanogaster pug 41279   NP_731489 62
N.crassa NCU03877 3872688   XP_956550 61
S.cerevisiae ADE3 853118   NP_011720 59
S.pombe SPBC839.16 2541217   NP_595256 59

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)