Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Sirt2, sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)
Sequence ID:NM_001122765
NM_001122766
NM_022432
Entrez Gene ID:64383
Ensembl ID:ENSMUSG00000015149

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, limb, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, pancreas, pancreatic islet, pituitary gland, placenta, pooled tissue, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7|7 B1-2

Chromosomal Position (from UCSC)

Chromosomal Position:7: 28766849 - 28788070

 Exon Info From UCSC:
NM_001122765
NM_001122766
NM_022432

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5039278Full LengthBC021439sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_071877  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001122765 NP_001116237    
NM_001122766 NP_001116238    
NM_007889 NP_031915 Q61062 PDZ
DEP
DIX
Dishevelled
NM_022432 NP_071877 Q8VDQ8 SIR2

Related Sequences

 
mRNAGenPeptSwissProt
U41285 AAB01761 Q61062
AF299337 AAG39256 Q8VDQ8
BC021439 AAH21439 Q8VDQ8
BC148469 AAI48470  
BC153065 AAI53066  
AK014042 BAB29128 Q8VDQ8
AK220155 BAD90341 Q571N4
AK146412 BAE27149 Q3UJK6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Sirt2 NP_071877 R.norvegicus Sirt2 361532   NP_001008369 97
H.sapiens SIRT2 22933 Gene Info NP_036369 88
D.melanogaster Sirt2 42414   NP_650880 55
A.gambiae AgaP_AGAP002943 1273019   XP_311957 53
N.crassa NCU00523 3879874   XP_963725 51
S.pombe hst2 2538868   NP_588147 50
S.cerevisiae HST2 856092   NP_015310 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)