Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Pik3ca, phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
Sequence ID:NM_008839
Entrez Gene ID:18706
Ensembl ID:ENSMUSG00000027665

Database Links

UniGeneEntrez GeneEnsembl GeneSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone marrow, brain, cerebellum, cerebrum, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, peripheral nervous system, pineal gland, placenta, pooled tissue, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3 B|3 12.4 cM

Chromosomal Position (from UCSC)

Chromosomal Position:3: 32464770 - 32466104

 Exon Info From UCSC:
NM_008839

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30692343Full LengthBC089038phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
40141870Full LengthBC130228phosphatidylinositol 3-kinase, catalytic, alpha polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_032865  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_008839 NP_032865 P42337 EC 2.7.11.1
EC 2.7.1.153
PI3_PI4_kinase
PI3Ka
PI3K_C2
PI3K_rbd
PI3K_p85B

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U03279 AAA18334 P42337 EC 2.7.11.1
EC 2.7.1.153
BC089038 AAH89038 P42337 EC 2.7.11.1
EC 2.7.1.153
BC130228 AAI30229 P42337 EC 2.7.11.1
EC 2.7.1.153

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Pik3ca NP_032865 H.sapiens PIK3CA 5290 Gene Info NP_006209 99
R.norvegicus Pik3ca 170911   XP_001063573 99
C.elegans age-1 174762   NP_496462 32

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta