Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Mm. Sirt6, Sirtuin 6 (silent mating type information regulation 2, homolog) 6 (S. cerevisiae)
Sequence ID:NM_181586
Entrez Gene ID:50721
Ensembl ID:ENSMUSG00000034748

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:10 C1|10 43.0

Chromosomal Position (from UCSC)

Chromosomal Position:10: 81621788 - 81627557

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6513375Full LengthBC052763sirtuin 6 (silent mating type information regulation 2, homolog) 6 (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_853617  

Protein Infomation

NM_001163430 NP_001156902    
NM_181586 NP_853617 P59941 SIR2

Related Sequences

BC052763 AAH52763 P59941
AK145929 BAE26760 Q3UKP1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
M.musculus Sirt6 NP_853617 R.norvegicus Sirt6 299638   NP_001026819 95
H.sapiens SIRT6 51548 Gene Info NP_057623 89
A.gambiae AgaP_AGAP001458 1281717   XP_321669 57
A.thaliana SRT1 835670   NP_200387 53
D.melanogaster Sirt6 41254   NP_649990 52
N.crassa NCU07624 3878947   XP_962799 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)