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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Map2k1, mitogen-activated protein kinase kinase 1
Sequence ID:NM_008927
Entrez Gene ID:26395
Ensembl ID:ENSMUSG00000004936

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, bone marrow, brain, cerebrum, colon, ear, embryonic tissue, eye, fetus, gastrointestinal tract, heart, kidney, limb, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, testis, thymus, uncharacterized tissue, uterus
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:9 C|9 36.0 cM

Chromosomal Position (from UCSC)

Chromosomal Position:9: 64186011 - 64253585

 Exon Info From UCSC:
NM_008927

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6411664Full LengthBC054754mitogen-activated protein kinase kinase 1
6589911IncompleteBC051137mitogen activated protein kinase kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_032953  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_008927 NP_032953 P31938
Q3TMJ8
EC 2.7.12.2 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L02526 AAA39523 P31938
Q3TMJ8
EC 2.7.12.2
BC054754 AAH54754 P31938
Q3TMJ8
EC 2.7.12.2
AB041567 BAA95051 Q9JJE1  
AK146233 BAE26999 Q3UK05  
AK146931 BAE27542 P31938
Q3TMJ8
EC 2.7.12.2
AK154793 BAE32832 Q3U3F4  
AK165664 BAE38326 Q3TMW4  
AK165894 BAE38443 P31938
Q3TMJ8
EC 2.7.12.2
AK167336 BAE39437 P31938
Q3TMJ8
EC 2.7.12.2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Map2k1 NP_032953 R.norvegicus Map2k1 170851   NP_113831 100
H.sapiens MAP2K1 5604 Gene Info NP_002746 99
A.gambiae AgaP_AGAP001103 1282062   XP_322064 69
D.melanogaster Dsor1 31872   NP_511098 67
C.elegans mek-2 171872   NP_491087 55
A.thaliana MEK1 828713   NP_194337 44
A.thaliana MKK2 829103   NP_001031751 44
S.cerevisiae STE7 851396   NP_010122 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta