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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Idh2, isocitrate dehydrogenase 2 (NADP+), mitochondrial
Sequence ID:NM_173011
Entrez Gene ID:269951
Ensembl ID:ENSMUSG00000030541

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, bone marrow, brain, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, vascular
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7 D3|7 41.0 cM

Chromosomal Position (from UCSC)

Chromosomal Position:7: 80094846 - 80115321

 Exon Info From UCSC:
NM_173011

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6515657Full LengthBC060030isocitrate dehydrogenase 2 (NADP+), mitochondrial

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_766599  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_173011 NP_766599 P54071 EC 1.1.1.42 Iso_dh

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF212319 AAG43538 P54071 EC 1.1.1.42
BC060030 AAH60030 P54071 EC 1.1.1.42
AK088110 BAC40149 P54071 EC 1.1.1.42
AK145753 BAE26628 P54071 EC 1.1.1.42
AK161640 BAE36505 P54071 EC 1.1.1.42
AK169395 BAE41142 P54071 EC 1.1.1.42

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Idh2 NP_766599 R.norvegicus Idh2 361596   NP_001014183 99
H.sapiens IDH2 3418 Gene Info NP_002159 95
A.gambiae AgaP_AGAP003168 1273838   XP_312860 74
C.elegans C34F6.8 181311   NP_509875 72
A.thaliana ICDH 841875   NP_175836 69
S.cerevisiae IDP3 855723   NP_014389 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)