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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Dhfr, dihydrofolate reductase
Sequence ID:NM_010049
Entrez Gene ID:13361
Ensembl ID:ENSMUSG00000021707

Database Links

UniGeneEntrez GeneEnsembl GeneSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:13 C3|13 43.0 cM

Chromosomal Position (from UCSC)

Chromosomal Position:13: 92387794 - 92389130

NM_010049 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
15629312473793125298
5636129312560493125653
6137189312788193127986
7198459313561993135745
8469619313813993138254
96252909315467993159007

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3707582Full LengthBC005796dihydrofolate reductase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_034179  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_010049 NP_034179 P00375
Q544T5
EC 1.5.1.3 DHFR_1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L26316 AAA37523 P00375
Q544T5
EC 1.5.1.3
M10722 AAA37524 P00375 EC 1.5.1.3
M10811 AAA37525 P00375 EC 1.5.1.3
BC005796 AAH05796 P00375
Q544T5
EC 1.5.1.3
AK031241 BAC27315 P00375
Q544T5
EC 1.5.1.3
AK136212 BAE22879 P00375
Q544T5
EC 1.5.1.3
V00734 CAA24112 P00375 EC 1.5.1.3
X56066 CAA39544 P00375 EC 1.5.1.3
V00731 CAB43539 P00375 EC 1.5.1.3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Dhfr NP_034179 R.norvegicus Dhfr 24312   NP_569084 97
H.sapiens DHFR 1719 Gene Info NP_000782 90
D.melanogaster Dhfr 42003   NP_001036720 51
A.gambiae AgaP_AGAP010278 1279701   XP_319471 45
C.elegans dhfr-1 172681   NP_492364 37
S.cerevisiae DFR1 854411   NP_014879 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta