Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Htra2, HtrA serine peptidase 2
Sequence ID:NM_019752
Entrez Gene ID:64704
Ensembl ID:ENSMUSG00000068329

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, limb, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, peripheral nervous system, pituitary gland, pooled tissue, retina, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue, uterus
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:6 C3|6 34.75 cM

Chromosomal Position (from UCSC)

Chromosomal Position:6: 83051281 - 83054435

NM_019752 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
183838300126283001627
3844798300173583001830
4805498300246683002535
5506558300269183002796
6566888300303183003063
6898838300332283003516
88410888300360683003810
108917398300391483004564

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5321861Full LengthBC049880HtrA serine peptidase 2
4217007IncompleteBC033276HtrA serine peptidase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_062726  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_019752 NP_062726 Q9JIY5
Q80V84
EC 3.4.21.108 Trypsin
PDZ

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF175324 AAD50499 Q9JIY5 EC 3.4.21.108
AF164513 AAF89534 Q9JIY5 EC 3.4.21.108
BC049880 AAH49880 Q80V84  
AK146338 BAE27092 Q3UJR3  
AK159188 BAE34885 Q3TXN0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Htra2 NP_062726 R.norvegicus Htra2 297376   NP_001100069 94
H.sapiens HTRA2 27429 Gene Info NP_037379 85
A.gambiae AgaP_AGAP000240 1272021   XP_310886 59
D.melanogaster HtrA2 41756   NP_650366 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)