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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Mm. Ncstn, nicastrin
Sequence ID:NM_021607
Entrez Gene ID:59287
Ensembl ID:ENSMUSG00000003458

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, kidney, limb, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1 H3|1 93.5 cM

Chromosomal Position (from UCSC)

Chromosomal Position:1: 172066567 - 172082699

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4458780Full LengthBC019998nicastrin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_067620  

Protein Infomation

NM_021607 NP_067620 P57716 Nicastrin

Related Sequences

AF240469 AAG11413 P57716
BC019998 AAH19998 P57716
AK129102 BAC97912 Q6ZQF2
AK160338 BAE35745 Q3TV74
AK170244 BAE41658 Q3TDE4
AK170369 BAE41750 Q3TD54
AK172579 BAE43077 Q3T9E5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
M.musculus Ncstn NP_067620 R.norvegicus Ncstn 289231   NP_777353 96
H.sapiens NCSTN 23385 Gene Info NP_056146 89
D.melanogaster nct 42964   NP_001163713 34
A.gambiae AgaP_AGAP001734 1281441   XP_321352 34
A.thaliana AT3G52640 824430   NP_974419 27
C.elegans aph-2 172905   NP_492712 25

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)