Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Mm. Top1, topoisomerase (DNA) I
Sequence ID:NM_009408
Entrez Gene ID:21969
Ensembl ID:ENSMUSG00000070544

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:2 H2-3|2 92.0 cM

Chromosomal Position (from UCSC)

Chromosomal Position:2: 160722623 - 160722764

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100069495Full LengthBC172687topoisomerase (DNA) I
3491052IncompleteBC002095topoisomerase (DNA) I
4946857IncompleteBC092349topoisomerase (DNA) I
100062641BC156379topoisomerase (DNA) I

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_033434  

Protein Infomation

NM_009408 NP_033434 Q04750 EC Topoisom_I

Related Sequences

L20632 AAA40466 Q04750 EC
BC092349 AAH92349 Q569Q5  
BC156379 AAI56380    
BC172687 AAI72687    
D10061 BAA00950 Q04750 EC
AK145538 BAE26493 Q3ULF5  
AK160590 BAE35897 Q3TUS4  
AK161863 BAE36613 Q3TSR2  
AK164061 BAE37608 Q3TPX7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
M.musculus Top1 NP_033434 R.norvegicus Top1 64550   NP_072137 99
H.sapiens TOP1 7150 Gene Info NP_003277 97
A.gambiae AgaP_AGAP004078 1270877   XP_309629 62
D.melanogaster Top1 32458   NP_001014742 61
C.elegans top-1 266847   NP_493337 60
S.cerevisiae TOP1 854156   NP_014637 51
N.crassa NCU09118 3874180   XP_958033 46
A.thaliana TOP1BETA 835624   NP_200342 44
S.pombe top1 2540032   NP_596209 44
A.thaliana TOP1ALPHA 835623   NP_200341 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)