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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Mdh1, malate dehydrogenase 1, NAD (soluble)
Sequence ID:NM_008618
Entrez Gene ID:17449
Ensembl ID:ENSMUSG00000020321

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone marrow, brain, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, limb, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11 A3.1|11 12.0 cM

Chromosomal Position (from UCSC)

Chromosomal Position:11: 21556786 - 21571812

NM_008618 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
18772145669421457570
8789672145846421458553
96810812145919421459307
108212582145970121459877
125913812146286721462989
138215572146404321464218
155816542146582621465922
165517532146662221466720
175419582147173221471936

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6820601Full LengthBC050940malate dehydrogenase 1, NAD (soluble)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_032644  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_008618 NP_032644 P14152 EC 1.1.1.37 Ldh_1_N
Ldh_1_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M29462 AAA39510 P14152 EC 1.1.1.37
BC050940 AAH50940 P14152 EC 1.1.1.37
AK005237 BAB23897 P14152 EC 1.1.1.37
AK164785 BAE37915 P14152 EC 1.1.1.37
AK168545 BAE40421 P14152 EC 1.1.1.37

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Mdh1 NP_032644 R.norvegicus Mdh1 24551   NP_150238 99
H.sapiens MDH1 4190 Gene Info NP_001186040 96
D.melanogaster CG5362 34414   NP_609394 66
A.gambiae AgaP_AGAP009510 1271401   XP_310186 66
A.thaliana AT5G43330 834351   NP_199147 62
A.thaliana AT1G04410 839527   NP_171936 62
C.elegans F46E10.10 179041   NP_504656 60

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta