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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Mm. Top2b, topoisomerase (DNA) II beta
Sequence ID:NM_009409
Entrez Gene ID:21974
Ensembl ID:ENSMUSG00000017485

Database Links

UniGeneEntrez GeneEnsembl GeneVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Expression Matrix

  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14|14 A3

Chromosomal Position (from UCSC)

Chromosomal Position:14: 16365178 - 16398758

 Exon Info From UCSC:
NM_009409

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5368508Full LengthBC041106topoisomerase (DNA) II beta
6406462Full LengthBC054541topoisomerase (DNA) II beta

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_033435  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_009409 NP_033435 Q64511 EC 5.99.1.3 DNA_gyraseB
DNA_topoisoIV
HATPase_c
DTHCT

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC041106 AAH41106 Q64511 EC 5.99.1.3
BC054541 AAH54541 Q64511 EC 5.99.1.3
D38046 BAA07236 Q64511 EC 5.99.1.3
AK041054 BAC30801 Q8BRY5  
AK163043 BAE37168 Q3TR62  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
M.musculus Top2b NP_033435 H.sapiens TOP2B 7155 Gene Info NP_001059 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta