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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SRD5A2, steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
Sequence ID:NM_000348
RefSeqGene ID:NG_008365
Entrez Gene ID:6716

Database Links

UniGeneEntrez GeneOMIMHPRDSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
PSEUDOVAGINAL PERINEOSCROTAL HYPOSPADIAS 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 31750961 - 31935339

NM_000348 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
116773174965531751331
167818283175437631754526
182919303175644031756541
193120943175867231758835
209522853180568931805879
228724463180588031806039

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8322693Full LengthBC113641steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
8327720Full LengthBC112252steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000339  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000348 NP_000339   Steroid_dh

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M74047 AAA60586 P31213 EC 1.3.1.30
BC112252 AAI12253 P31213 EC 1.3.1.30
BC113641 AAI13642 P31213 EC 1.3.1.30
EF560740 ABQ59050 P31213 EC 1.3.1.30
EU832809 ACE87820    
GQ129244 ACT64378    
HQ258121 ADR82875    
AK316597 BAG38184 P31213 EC 1.3.1.30

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SRD5A2 NP_000339 R.norvegicus Srd5a2 64677   NP_073202 78
M.musculus Srd5a2 94224 Gene Info NP_444418 75

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)