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Gene Info

Gene Information For:Hs. NF2, neurofibromin 2 (merlin)
Sequence ID:NM_000268
NM_016418
NM_181825
NM_181828
NM_181829
NM_181830
NM_181831
NM_181832
NM_181833
NM_181826
NM_181827
NM_181834
NM_181835
RefSeqGene ID:NG_009057
Entrez Gene ID:4771
Ensembl ID:ENSG00000186575

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MENINGIOMAMN1
PTEN
SUFU
NEUROFIBROMATOSIS, TYPE 2 
SCHWANNOMATOSIS 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q12.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 30093555 - 30094585

 Exon Info From UCSC:
NM_000268
NM_016418
NM_181825
NM_181828
NM_181829
NM_181830
NM_181831
NM_181832
NM_181833

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3537045Full LengthBC003112neurofibromin 2 (merlin)
4871980Full LengthBC020257neurofibromin 2 (merlin)
3343280IncompleteBC007279neurofibromin 2 (merlin)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_861546  NP_861970  NP_861969  NP_861967  NP_000259  NP_861968  NP_861966  NP_057502  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000268 NP_000259 P35240 Band_41
ERM
NM_016418 NP_057502   Band_41
ERM
NM_181825 NP_861546   Band_41
ERM
NM_181828 NP_861966   Band_41
ERM
NM_181829 NP_861967   Band_41
ERM
NM_181830 NP_861968   Band_41
ERM
NM_181831 NP_861969   Band_41
ERM
NM_181832 NP_861970   Band_41
ERM
NM_181833 NP_861971    

Related Sequences

 
mRNAGenPeptSwissProt
L11353 AAA36212 P35240
L27065 AAA62422 Q7KZ66
S73853 AAB31736 Q16230
S73854 AAB31737 Q16231
S73856 AAB31738 Q16233
AF122827 AAD48752 P35240
AF122828 AAD48753 P35240
AF123570 AAD48754 P35240
AF113694 AAF29587 Q9P1N4
BC003112 AAH03112 P35240
BC020257 AAH20257 P35240
AF369657 AAK54160 P35240
AF369658 AAK54161 P35240
AF369661 AAK54162 P35240
AF369662 AAK54163 P35240
AF369663 AAK54164 P35240
AF369664 AAK54165 P35240
AF369665 AAK54166 P35240
AF369700 AAK54195 P35240
AF369701 AAK54196 P35240
DQ891697 ABM82623  
DQ894878 ABM85804  
EF517524 ABP73252 A5A158
AK297116 BAH12502 B7Z4B6
Z22664 CAA80377 P35240
CR456530 CAG30416 P35240
CU013130 CAK54561  
CU013418 CAK54860  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NF2 NP_000259 M.musculus Nf2 18016 Gene Info NP_035028 98
R.norvegicus Nf2 25744   NP_037325 98
A.gambiae AgaP_AGAP010346 1272693   XP_311595 58
D.melanogaster Mer 32979   NP_523413 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)