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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ELANE, Elastase, neutrophil expressed
Sequence ID:NM_001972
RefSeqGene ID:NG_009627
Entrez Gene ID:1991
Ensembl ID:ENSG00000197561

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
NEUTROPENIA, CYCLIC 
NEUTROPENIA, SEVERE CONGENITAL 1,AUTOSOMAL DOMINANTGFI1

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 852291 - 856221

NM_001972 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1105852290852394
106262852875853031
263404853261853402
405635855563855793
636922855957856243

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915320Full LengthBC074817elastase 2, neutrophil
30915534Full LengthBC074816elastase 2, neutrophil

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001963  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001972 NP_001963 P08246 EC 3.4.21.37 Trypsin

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M27783 AAA35792 P08246 EC 3.4.21.37
M34379 AAA36173 P08246 EC 3.4.21.37
J03545 AAA52378 P08246 EC 3.4.21.37
BC074816 AAH74816 P08246 EC 3.4.21.37
BC074817 AAH74817 P08246 EC 3.4.21.37
D00187 BAA00128 P08246 EC 3.4.21.37
X05875 CAA29299 P08246 EC 3.4.21.37
X05875 CAA29300 P08246 EC 3.4.21.37

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ELANE NP_001963 M.musculus Elane 50701 Gene Info NP_056594 74
R.norvegicus Elane 299606   NP_001100237 73

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta