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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. AURKC, aurora kinase C
Sequence ID:NM_001015878
NM_001015879
NM_003160
RefSeqGene ID:NG_012134
Entrez Gene ID:6795
Ensembl ID:ENSG00000105146

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
SPERMATOGENIC FAILURE 5 

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.43Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 57742458 - 57746806

 Exon Info From UCSC:
NM_001015878
NM_001015879
NM_003160

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30915373Full LengthBC075064aurora kinase C

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001015879  NP_003151  NP_001015878  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001015878 NP_001015878 Q9UQB9 EC 2.7.11.1 Pkinase
NM_001015879 NP_001015879     Pkinase
NM_003160 NP_003151     Pkinase
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF054621 AAC25955 Q9UQB9 EC 2.7.11.1
AF059681 AAC77369 Q9UQB9 EC 2.7.11.1
BC075064 AAH75064 Q9UQB9 EC 2.7.11.1
AY661554 AAT64422 Q9UQB9 EC 2.7.11.1
AY714054 AAU04399 Q5Y191  
AB017332 BAA76292 Q9UQB9 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AURKC NP_001015878 M.musculus Aurkc 20871 Gene Info NP_001074434 80
A.gambiae AgaP_AGAP007855 1278103   XP_317640 57
D.melanogaster ial 34504   NP_477336 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)