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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. DROSHA, drosha, ribonuclease type III
Sequence ID:NM_001100412
NM_013235
Entrez Gene ID:29102
Ensembl ID:ENSG00000113360

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 31401259 - 31472297

 Exon Info From UCSC:
NM_001100412
NM_013235

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6148714Full LengthBC054003ribonuclease type III, nuclear
3631271IncompleteBC024261ribonuclease III, nuclear
5114643IncompleteBC041162ribonuclease type III, nuclear

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_037367  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001100412 NP_001093882      
NM_013235 NP_037367 Q9NRR4 EC 3.1.26.3 dsrm
Ribonuclease_3

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF116910 AAD29637 Q9NRR4 EC 3.1.26.3
AF189011 AAF80558 Q9NRR4 EC 3.1.26.3
BC041162 AAH41162 Q9NRR4 EC 3.1.26.3
BC054003 AAH54003 Q9NRR4 EC 3.1.26.3
AK001121 BAA91511 Q9NRR4 EC 3.1.26.3
AB209501 BAD92738 Q59FF9  
AJ242976 CAB45133 Q9NRR4 EC 3.1.26.3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DROSHA NP_037367 M.musculus Drosha 14000 Gene Info NP_001123621 96
A.gambiae AgaP_AGAP008087 1277864   XP_555381 52
D.melanogaster drosha 35747   NP_477436 52
C.elegans drsh-1 172830   NP_001122460 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)