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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SH3GL1, SH3-domain GRB2-like 1
Sequence ID:NM_001199943
NM_001199944
NM_003025
RefSeqGene ID:NG_028084
Entrez Gene ID:6455
Ensembl ID:ENSG00000141985

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKEMIA, ACUTE MYELOGENOUSARHGEF12
CBFB
CEBPA
CHIC2
ETV6
FLT3
GATA2
GMPS
JAK2
KIT
LPP
MLF1
MLLT10
NPM1
NSD1
NUP214
PICALM
RUNX1
RUNX1
TERT
WHSC1L1

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 4360367 - 4400415

Transcript StartTranscript EndChromosomal Start Chromosomal End
19144443603674361792
1445150143623254362381
1502162643626084362732
1627173043633664363469
1731188943637164363874
1890202343640844364217
2024216743654784365621
2168224043664974366569
2241230943669224366990
2310246044003204400470

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3458016Full LengthBC001270SH3-domain GRB2-like 1
30561140Full LengthBC098565SH3-domain GRB2-like 1
3505990IncompleteBC014387SH3-domain GRB2-like 1
3506791IncompleteBC001094SH3-domain GRB2-like 1
3509447IncompleteBC000089SH3-domain GRB2-like 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003016  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001199943 NP_001186872    
NM_001199944 NP_001186873    
NM_003025 NP_003016 Q99961
Q6FGM0
SH3_1
BAR

Related Sequences

 
mRNAGenPeptSwissProt
U65999 AAB86800 Q99961
Q6FGM0
BC000089 AAH00089 Q9BWP4
BC001094 AAH01094 Q9BVL7
BC001270 AAH01270 Q99961
Q6FGM0
BC014387 AAH14387 Q9BVL7
BC098565 AAH98565 Q99961
Q6FGM0
AY364240 AAQ76799 Q99961
Q6FGM0
DQ891258 ABM82184  
DQ894444 ABM85370  
AK315450 BAG37838 Q6FGM0
AK299166 BAG61213 B4DRA1
X99656 CAA67970 Q99961
Q6FGM0
CR542087 CAG46884 Q99961
Q6FGM0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SH3GL1 NP_003016 M.musculus Sh3gl1 20405 Gene Info NP_038692 94
C.elegans unc-57 172078   NP_001122513 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)