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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. KCNQ1, potassium voltage-gated channel, KQT-like subfamily, member 1
Sequence ID:NM_000218
NR_040711
NM_181797
NM_181798
RefSeqGene ID:NG_008935
Entrez Gene ID:3784
Ensembl ID:ENSG00000053918

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ATRIAL FIBRILLATION, FAMILIAL, 3KCNE2
KCNE2
JERVELL AND LANGE-NIELSEN SYNDROMEKCNE1
KCNE1
LONG QT SYNDROME 1, ACQUIRED 
SHORT QT SYNDROME-2 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.5Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 2466220 - 2870221

 Exon Info From UCSC:
NM_000218
NM_181798

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8322597Full LengthBC113545potassium voltage-gated channel, KQT-like subfamily, member 1
3846095IncompleteBC017074potassium voltage-gated channel, KQT-like subfamily, member 1
40080835BC111847potassium voltage-gated channel, KQT-like subfamily, member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000209  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000218 NP_000209 P51787 Ion_trans
KCNQ_channel
NM_181798 NP_861463   Ion_trans
KCNQ_channel
Ion_trans_2

Related Sequences

 
mRNAGenPeptSwissProt
U86146 AAB53974 P51787
AF003743 AAC00066 O00550
AF051426 AAC05705 P51787
AF000571 AAC51776 P51787
U89364 AAC51781 P51787
BC017074 AAH17074 Q96AI9
BC111847 AAI11848  
BC113545 AAI13546 Q14D14
AY114213 AAM94040 P51787
EF010934 ABJ98773 A0FIK7
EF010935 ABJ98774 A0FIK8
HQ258460 ADR83214  
AK290618 BAF83307 Q14D14

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens KCNQ1 NP_000209 R.norvegicus Kcnq1 84020   NP_114462 91
M.musculus Kcnq1 16535 Gene Info NP_032460 90
C.elegans kqt-3 191699   NP_496875 60

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)