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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NKX2-1, NK2 homeobox 1
Sequence ID:NM_001079668
NM_003317
RefSeqGene ID:NG_013365
Entrez Gene ID:7080
Ensembl ID:ENSG00000136352

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:14q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 36985603 - 36989364

 Exon Info From UCSC:
NM_001079668
NM_003317

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3941576Full LengthBC006221NK2 homeobox 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003308  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001079668 NP_001073136    
NM_003317 NP_003308 P43699 Homeobox

Related Sequences

 
mRNAGenPeptSwissProt
U19756 AAA86099 P43699
U43203 AAA89066 P43699
U33749 AAB52381 P43699
BC006221 AAH06221 P43699
BT009773 AAP88775 P43699
DQ892964 ABM83890  
DQ896211 ABM87210  
D50741 BAA23528 O14956
D50740 BAA23529 P43699
X82850 CAA58053 P43699

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NKX2-1 NP_001073136 R.norvegicus Nkx2-1 25628   NP_037225 99
M.musculus Nkx2-1 21869 Gene Info NP_001139670 98
D.melanogaster scro 3355151   NP_001015473 54

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)