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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SCN2A, sodium channel, voltage-gated, type II, alpha subunit
Sequence ID:NM_001040142
NM_001040143
NM_021007
RefSeqGene ID:NG_008143
Entrez Gene ID:6326
Ensembl ID:ENSG00000136531

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
EPILEPTICENCEPHALOPATHY, EARLY INFANTILE, 11 
SEIZURES, BENIGN FAMILIAL INFANTILE, 3 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 166095911 - 166172108

 Exon Info From UCSC:
NM_001040142
NM_001040143
NM_021007

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9094251IncompleteBC172765sodium channel, voltage-gated, type II, alpha 2
9094252IncompleteBC172766sodium channel, voltage-gated, type II, alpha 2
9094283IncompleteBC172797sodium channel, voltage-gated, type II, alpha 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_066287  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001040142 NP_001035232    
NM_001040143 NP_001035233    
NM_021007 NP_066287 Q99250 Ion_trans
IQ
Na_trans_assoc

Related Sequences

 
mRNAGenPeptSwissProt
M94055 AAA18895 Q99250
GU014841 ACX32328  
AB208888 BAD92125 Q59H71
AK289656 BAF82345 A8K0U1
X65361 CAA46438 Q99250

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SCN2A NP_001035232 R.norvegicus Scn2a1 24766   NP_036779 98
M.musculus Scn2a1 110876 Gene Info NP_001092768 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)