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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. C8A, complement component 8, alpha polypeptide
Sequence ID:NM_000562
RefSeqGene ID:NG_012049
Entrez Gene ID:731
Ensembl ID:ENSG00000157131

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
C8 DEFICIENCY, TYPE I 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 57320468 - 57358645

 Exon Info From UCSC:
NM_000562

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40146933Full LengthBC132911complement component 8, alpha polypeptide
40146935Full LengthBC132913complement component 8, alpha polypeptide
4714726IncompleteBC020702complement component 8, alpha polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000553  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000562 NP_000553 P07357 Ldl_recept_a
TSP_1
MACPF

Related Sequences

 
mRNAGenPeptSwissProt
M16974 AAA52200 P07357
BC020702 AAH20702 Q05CV2
BC132911 AAI32912 P07357
BC132913 AAI32914 P07357
HQ258328 ADR83082  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens C8A NP_000553 R.norvegicus C8a 298288   NP_001100140 74
M.musculus C8a 230558 Gene Info NP_666260 73

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta