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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CASP7, caspase 7, apoptosis-related cysteine peptidase
Sequence ID:NM_001227
NM_001267056
NM_001267057
NM_001267058
NM_033338
NM_033339
NM_033340
Entrez Gene ID:840
Ensembl ID:ENSG00000165806

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 115451730 - 115489298

 Exon Info From UCSC:
NM_001227
NM_033338
NM_033339
NM_033340

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3921455Full LengthBC015799caspase 7, apoptosis-related cysteine peptidase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_203125  NP_001218  NP_203126  NP_203124  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001227 NP_001218 P55210 EC 3.4.22.60 Peptidase_C14
NM_001267056 NP_001253985      
NM_001267057 NP_001253986      
NM_001267058 NP_001253987      
NM_033338 NP_203124     Peptidase_C14
NM_033339 NP_203125 P55210 EC 3.4.22.60 Peptidase_C14
NM_033340 NP_203126     Peptidase_C14

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U37448 AAC50303 P55210 EC 3.4.22.60
U37449 AAC50304 P55210 EC 3.4.22.60
U39613 AAC50346 P55210 EC 3.4.22.60
U40281 AAC50352 P55210 EC 3.4.22.60
U67320 AAC51153 P55210 EC 3.4.22.60
U67206 AAF21460 P55210 EC 3.4.22.60
BC015799 AAH15799 P55210 EC 3.4.22.60
BT006683 AAP35329 P55210 EC 3.4.22.60
DQ893769 ABM84695    
DQ890614 ABM92231    
EU832034 ACE86696    
EU831939 ACE87380    
AK298964 BAG61059 B4DQU7  
AK300578 BAG62277 B4DUB5  
AK301437 BAG62964 B4DWA2  
AB451281 BAG70095 P55210 EC 3.4.22.60
AB451413 BAG70227 P55210 EC 3.4.22.60

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CASP7 NP_203124 R.norvegicus Casp7 64026   NP_071596 85
M.musculus Casp7 12369 Gene Info NP_031637 82
D.melanogaster Dcp-1 37729   NP_476974 46
D.melanogaster Ice 43514   NP_524551 45
A.gambiae CASPS7 1277339   XP_316795 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta