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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. GZMA, granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
Sequence ID:NM_006144
RefSeqGene ID:NG_027996
Entrez Gene ID:3001
Ensembl ID:ENSG00000145649

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q11-q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 54398502 - 54406080

NM_006144 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4849202Full LengthBC015739granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006135  

Protein Infomation

NM_006144 NP_006135 P12544 EC Trypsin

Related Sequences

M18737 AAA52647 P12544 EC
BC015739 AAH15739 P12544 EC
DQ893071 ABM83997    
DQ896326 ABM87325    
CR456968 CAG33249 P12544 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens GZMA NP_006135 R.norvegicus Gzma 266708   NP_703198 70
M.musculus Gzma 14938 Gene Info NP_034500 69

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta