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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. GZMA, Granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
Sequence ID:NM_006144
RefSeqGene ID:NG_027996
Entrez Gene ID:3001
Ensembl ID:ENSG00000145649

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:5q11-q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 54398502 - 54406080

NM_006144 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11075439847354398579
1082525440130154401445
2533945440362154403762
3956645440395254404221
6658955440584854406078

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4849202Full LengthBC015739granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006135  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006144 NP_006135 P12544 EC 3.4.21.78 Trypsin

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M18737 AAA52647 P12544 EC 3.4.21.78
BC015739 AAH15739 P12544 EC 3.4.21.78
DQ893071 ABM83997    
DQ896326 ABM87325    
CR456968 CAG33249 P12544 EC 3.4.21.78

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GZMA NP_006135 R.norvegicus Gzma 266708   NP_703198 70
M.musculus Gzma 14938 Gene Info NP_034500 69

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta