Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SPTLC1, serine palmitoyltransferase, long chain base subunit 1
Sequence ID:NM_006415
RefSeqGene ID:NG_007950
Entrez Gene ID:10558
Ensembl ID:ENSG00000090054

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q22.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 94813112 - 94877638

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5259635Full LengthBC068537serine palmitoyltransferase, long chain base subunit 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006406  

Protein Infomation

NM_006415 NP_006406 O15269 EC Aminotran_1_2
NM_178324 NP_847894      

Related Sequences

BC007085 AAH07085 O15269 EC
BC068537 AAH68537 Q6NUL7  
AB209757 BAD92994 Q59EQ4  
AK291546 BAF84235 O15269 EC
AK299153 BAG61202 B4DR90  
Y08685 CAA69941 O15269 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SPTLC1 NP_006406 M.musculus Sptlc1 268656 Gene Info NP_033295 92
R.norvegicus Sptlc1 361213   NP_001101876 91
A.gambiae AgaP_AGAP010427 1272620   XP_311520 54
C.elegans sptl-1 173389   NP_001021978 51
D.melanogaster Spt-I 36448   NP_610842 51
A.thaliana LCB1 829800   NP_001031796 45
S.pombe SPBC18E5.02c 2540820   NP_595848 39
N.crassa NCU06870 3874126   XP_957979 38
S.cerevisiae LCB1 855342   NP_014025 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)