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Gene Info

Gene Information For:Hs. NDUFS8, NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
Sequence ID:NM_002496
RefSeqGene ID:NG_017040
Entrez Gene ID:4728
Ensembl ID:ENSG00000110717

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, adrenal medulla, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
LEIGH SYNDROMEBCS1L
COX15
DLD
FOXRED1
NDUFA10
NDUFA12
NDUFA2
NDUFA9
NDUFAF2
NDUFAF6
NDUFS3
NDUFS4
NDUFS7
NDUFV1
SDHA
SURF1

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 67798179 - 67802749

NM_002496 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11176779808367798199
1181756779961867799675
1762266779975267799802
2273166780038967800478
3174896780057767800749
4906186780371967803847
6198046780392867804113

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40119290Full LengthBC119754NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002487  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002496 NP_002487 O00217 EC 1.6.99.3
EC 1.6.5.3
Fer4

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U65579 AAB51776 O00217 EC 1.6.99.3
EC 1.6.5.3
BC119753 AAI19754 Q08E91  
BC119754 AAI19755 O00217 EC 1.6.99.3
EC 1.6.5.3
AK223114 BAD96834 Q53G17  
AK314546 BAG37133 O00217 EC 1.6.99.3
EC 1.6.5.3
AK302449 BAG63745 B4DYI3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NDUFS8 NP_002487 M.musculus Ndufs8 225887 Gene Info NP_659119 91
R.norvegicus Ndufs8 293652   NP_001099792 91
A.gambiae AgaP_AGAP001711 1281463   XP_321378 86
D.melanogaster ND23 44207   NP_524719 83
A.thaliana AT1G79010 844242   NP_178022 79
A.thaliana AT1G16700 838239   NP_173114 79
N.crassa NCU05009 3872083   XP_955936 75
C.elegans T20H4.5 176023   NP_498595 70

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)