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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ATIC, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Sequence ID:NM_004044
RefSeqGene ID:NG_013002
Entrez Gene ID:471
Ensembl ID:ENSG00000138363

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q35Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 216176830 - 216214487

 Exon Info From UCSC:
NM_004044

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4300570Full LengthBC0088795-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004035  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004044 NP_004035 P31939 EC 3.5.4.10
EC 2.1.2.3
AICARFT_IMPCHas
MGS

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U37436 AAA97405 P31939 EC 3.5.4.10
EC 2.1.2.3
BC008879 AAH08879 P31939 EC 3.5.4.10
EC 2.1.2.3
DQ893262 ABM84188    
DQ896591 ABM87590    
D82348 BAA11559 P31939 EC 3.5.4.10
EC 2.1.2.3
D89976 BAA21762 P31939 EC 3.5.4.10
EC 2.1.2.3
AB062403 BAB93490 P31939 EC 3.5.4.10
EC 2.1.2.3
AK290067 BAF82756 A8K202  
AK313066 BAG35895 B2R7P8  
AK298142 BAG60418 B4DP06  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ATIC NP_004035 M.musculus Atic 108147 Gene Info NP_080471 91
R.norvegicus Atic 81643   NP_112276 91
D.melanogaster CG11089 42973   NP_001189286 71
A.gambiae AgaP_AGAP001423 1281753   XP_321707 69
S.cerevisiae ADE17 855149   NP_013839 62
N.crassa NCU02629 3880203   XP_964054 62
C.elegans transferase 177576   NP_741452 61
S.pombe ade10 2539569   NP_588027 61

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)