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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PDE4A, phosphodiesterase 4A, cAMP-specific
Sequence ID:NM_001111307
NM_001111308
NM_001111309
NM_001243121
NM_006202
RefSeqGene ID:NG_029594
Entrez Gene ID:5141
Ensembl ID:ENSG00000065989

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 10543110 - 10578297

 Exon Info From UCSC:
NM_001111307
NM_001111308
NM_001111309
NM_006202

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4942336Full LengthBC019864phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)
5732341Full LengthBC038234phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006193  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001111307 NP_001104777 P27815 EC 3.1.4.17  
NM_001111308 NP_001104778      
NM_001111309 NP_001104779      
NM_001243121 NP_001230050      
NM_006202 NP_006193     PDEase_I

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L20965 AAA03588 P27815 EC 3.1.4.17
M37744 AAA69697 P27815 EC 3.1.4.17
U18088 AAA98540 P27815 EC 3.1.4.17
S75213 AAB33798 P27815 EC 3.1.4.17
U97584 AAC25679 P27815 EC 3.1.4.17
U18087 AAC50458 P27815 EC 3.1.4.17
U68532 AAC63832 P27815 EC 3.1.4.17
AF073745 AAD34217 P27815 EC 3.1.4.17
BC019864 AAH19864 P27815 EC 3.1.4.17
BC038234 AAH38234 P27815 EC 3.1.4.17
AY266362 AAP31234 Q86V67  
AY593872 AAT00628 P27815 EC 3.1.4.17
AY618547 AAU82096 P27815 EC 3.1.4.17
DQ892448 ABM83374    
DQ895660 ABM86586    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PDE4A NP_001104777 R.norvegicus Pde4a 25638   NP_037233 86
M.musculus Pde4a 18577 Gene Info NP_899668 86

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)