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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PC, pyruvate carboxylase
Sequence ID:NM_000920
NM_001040716
NM_022172
RefSeqGene ID:NG_008319
Entrez Gene ID:5091
Ensembl ID:ENSG00000173599

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
PYRUVATE CARBOXYLASE DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13.4-q13.5Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 66627888 - 66725847

 Exon Info From UCSC:
NM_000920
NM_001040716
NM_022172

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3946441Full LengthBC011617pyruvate carboxylase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000911  NP_071504  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000920 NP_000911     CPSase_L_chain
Biotin_lipoyl
HMGL-like
PYC_OADA
Biotin_carb_C
CPSase_L_D2
NM_001040716 NP_001035806      
NM_022172 NP_071504 P11498 EC 6.4.1.1 CPSase_L_chain
Biotin_lipoyl
HMGL-like
PYC_OADA
Biotin_carb_C
CPSase_L_D2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M26122 AAA36423 P11498 EC 6.4.1.1
K02282 AAA60033 P11498 EC 6.4.1.1
U30891 AAA82937 P11498 EC 6.4.1.1
U04641 AAA99537 P11498 EC 6.4.1.1
S72370 AAB31500 P11498 EC 6.4.1.1
BC011617 AAH11617 P11498 EC 6.4.1.1
AK297705 BAG60062 B4DN00  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PC NP_000911 M.musculus Pcx 18563 Gene Info NP_001156418 97
R.norvegicus Pc 25104   NP_036876 96
A.gambiae AgaP_AGAP004742 1278483   XP_001689096 69
D.melanogaster CG1516 36020   NP_724841 69
C.elegans pyc-1 179616   NP_505977 66
S.cerevisiae PYC2 852519   NP_009777 55
N.crassa NCU02505 3881786   XP_965636 55
S.cerevisiae PYC1 852818   NP_011453 55
S.pombe pyr1 2539661   NP_595900 54

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta