Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PSMB4, proteasome (prosome, macropain) subunit, beta type, 4
Sequence ID:NM_002796
Entrez Gene ID:5692
Ensembl ID:ENSG00000159377

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 151372040 - 151373603

NM_002796 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1163151372040151372202
164370151372456151372662
371517151372917151373063
518599151373239151373320
600716151373714151373830
717805151374017151374105
806925151374292151374411

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822513IncompleteBC000331proteasome (prosome, macropain) subunit, beta type, 4
2967687IncompleteBC010088proteasome (prosome, macropain) subunit, beta type, 4
3143023IncompleteBC008314proteasome (prosome, macropain) subunit, beta type, 4
3505166IncompleteBC010098proteasome (prosome, macropain) subunit, beta type, 4
3536964IncompleteBC017486proteasome (prosome, macropain) subunit, beta type, 4
3543917IncompleteBC017451proteasome (prosome, macropain) subunit, beta type, 4
3607881IncompleteBC011768proteasome (prosome, macropain) subunit, beta type, 4
4640238IncompleteBC012168proteasome (prosome, macropain) subunit, beta type, 4
5088267IncompleteBC017307proteasome (prosome, macropain) subunit, beta type, 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002787  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002796 NP_002787 P28070 EC 3.4.25.1 Proteasome

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
S71381 AAB31085 P28070 EC 3.4.25.1
BT006917 AAP35563 P28070 EC 3.4.25.1
DQ890748 ABM81674    
DQ892020 ABM82946    
DQ895212 ABM86138    
D26600 BAA05647 P28070 EC 3.4.25.1
AK313825 BAG36560 P28070 EC 3.4.25.1
AK294149 BAG57474 B4DFL3  
CR456820 CAG33101 P28070 EC 3.4.25.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PSMB4 NP_002787 M.musculus Psmb4 19172 Gene Info NP_032971 94
R.norvegicus Psmb4 58854   NP_113817 93
A.gambiae AgaP_AGAP011444 1278250   XP_317860 48
A.gambiae AgaP_AGAP012608 1268428   XP_306986 48
A.thaliana PBG1 842098   NP_176040 46
N.crassa NCU07365 3874140   XP_957993 46
S.cerevisiae PRE4 850611   NP_116708 45
S.pombe SPBC577.10 2540875   NP_595308 44
D.melanogaster Prosbeta7 40639   NP_730922 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)