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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LMNB1, lamin B1
Sequence ID:NM_001198557
NM_005573
RefSeqGene ID:NG_008360
Entrez Gene ID:4001
Ensembl ID:ENSG00000113368

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKODYSTROPHY, ADULT-ONSET, AUTOSOMAL DOMINANT 

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q23.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 126112844 - 126172263


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3445475Full LengthBC012295lamin B1
6146212Full LengthBC103723lamin B1
6503792IncompleteBC078178lamin B1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005564  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001198557 NP_001185486    
NM_005573 NP_005564 P20700 Filament
IF_tail

Related Sequences

 
mRNAGenPeptSwissProt
M34458 AAA36162 P20700
BC012295 AAH12295 P20700
BC078178 AAH78178 Q6DC98
BC103723 AAI03724 P20700
DQ891592 ABM82518  
EU176582 ABW03383  
AK312603 BAG35493 P20700
AK303084 BAG64195 B4DZT3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LMNB1 NP_005564 M.musculus Lmnb1 16906 Gene Info NP_034851 96
R.norvegicus Lmnb1 116685   NP_446357 96
A.gambiae AgaP_AGAP011938 1280731   XP_320593 38
D.melanogaster Lam 33782   NP_476616 38
C.elegans lmn-1 172687   NP_492371 34

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta