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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HDAC1, histone deacetylase 1
Sequence ID:NM_004964
Entrez Gene ID:3065
Ensembl ID:ENSG00000116478

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 32757770 - 32798643

 Exon Info From UCSC:
NM_004964

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820260Full LengthBC000301histone deacetylase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004955  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004964 NP_004955 Q13547
Q6IT96
EC 3.5.1.98 Hist_deacetyl

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U50079 AAC50475 Q13547
Q6IT96
EC 3.5.1.98
BC000301 AAH00301 Q13547
Q6IT96
EC 3.5.1.98
AY627042 AAT44863 Q13547
Q6IT96
EC 3.5.1.98
DQ891398 ABM82324    
DQ894577 ABM85503    
D50405 BAA08909 Q13547 EC 3.5.1.98
AK299241 BAG61272 B4DRG0  
AK299792 BAG61671 B4DSK9  
AB451297 BAG70111 B5BU61  
AB451430 BAG70244 Q6IT96  
AK296308 BAH12310 B7Z3S4  
CR541717 CAG46518 Q13547
Q6IT96
EC 3.5.1.98
BX648055 CAI46269 Q5HYD4  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HDAC1 NP_004955 M.musculus Hdac1 433759 Gene Info NP_032254 99
R.norvegicus Hdac1 297893   NP_001020580 99
A.gambiae AgaP_AGAP006511 1277106   XP_316539 79
D.melanogaster Rpd3 38565   NP_647918 77
C.elegans hda-1 179959   NP_506599 65
S.cerevisiae RPD3 855386   NP_014069 64
N.crassa NCU00824 3880510   XP_964367 63
S.pombe clr6 2540368   NP_595333 63
A.thaliana HDA9 823594   NP_190054 61

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta