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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. DICER1, dicer 1, ribonuclease type III
Sequence ID:NM_001195573
NM_030621
NM_177438
NM_001271282
RefSeqGene ID:NG_016311
Entrez Gene ID:23405
Ensembl ID:ENSG00000100697

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q32.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 95556804 - 95623759

 Exon Info From UCSC:
NM_030621
NM_177438

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8860125Full LengthBC150287dicer 1, ribonuclease type III
4820771IncompleteBC068591Dicer1, Dcr-1 homolog (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_085124  NP_803187  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001195573 NP_001182502    
NM_001271282 NP_001258211    
NM_030621 NP_085124 Q9UPY3 dsrm
DEAD
Helicase_C
Ribonuclease_3
PAZ
DUF283
ResIII
NM_177438 NP_803187   dsrm
DEAD
Helicase_C
Ribonuclease_3
PAZ
DUF283
ResIII

Related Sequences

 
mRNAGenPeptSwissProt
BC150287 AAI50288 Q9UPY3
AY845867 AAW31883  
AY929254 AAX18334 Q5D0K5
AY929255 AAX18335 Q5D0K5
AY929256 AAX18336 Q5D0K4
HM595745 ADK25182 Q9UPY3
AB023145 BAA76772 Q9UPY3
AB028449 BAA78691 Q9UPY3
AK002007 BAG51002 B3KMJ0
AK091513 BAG52376 B3KRG4
AJ132261 CAB38857 Q9UPY3
AL122105 CAB59269 Q9UFF3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DICER1 NP_803187 R.norvegicus Dicer1 299284   XP_001068155 94
M.musculus Dicer1 192119 Gene Info NP_683750 93
C.elegans dcr-1 176138   NP_498761 44
A.thaliana DCL2 821300   NP_001189798 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta