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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. GCH1, GTP cyclohydrolase 1
Sequence ID:NM_000161
NM_001024024
NM_001024070
NM_001024071
RefSeqGene ID:NG_008647
Entrez Gene ID:2643
Ensembl ID:ENSG00000131979

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:14q22.1-q22.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 55309709 - 55313842

 Exon Info From UCSC:
NM_000161
NM_001024024
NM_001024070
NM_001024071

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4129035Full LengthBC025415GTP cyclohydrolase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000152  NP_001019195  NP_001019241  NP_001019242  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000161 NP_000152 P30793 EC 3.5.4.16 GTP_cyclohydroI
NM_001024024 NP_001019195 P30793 EC 3.5.4.16 GTP_cyclohydroI
NM_001024070 NP_001019241     GTP_cyclohydroI
NM_001024071 NP_001019242     GTP_cyclohydroI

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U19523 AAB16861 P30793 EC 3.5.4.16
S44049 AAB23164 P30793 EC 3.5.4.16
S44053 AAB23165 P30793 EC 3.5.4.16
S43856 AAB23166 P30793 EC 3.5.4.16
U66095 AAD38866 P30793 EC 3.5.4.16
U66097 AAD38868 P30793 EC 3.5.4.16
BC025415 AAH25415 P30793 EC 3.5.4.16
AF321276 AAK51704 Q96T74  
AY137463 AAN17459 Q8IZH9  
AY137464 AAN17460 Q8IZH8  
AY137465 AAN17461 Q8IZH7  
DQ892998 ABM83924    
DQ896245 ABM87244    
Z16418 CAA78908 P30793 EC 3.5.4.16
Z29433 CAB77391 P30793 EC 3.5.4.16
Z29434 CAB77392 P30793 EC 3.5.4.16
CR536551 CAG38788 P30793 EC 3.5.4.16

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GCH1 NP_000152 R.norvegicus Gch1 29244   NP_077332 93
M.musculus Gch1 14528 Gene Info NP_032128 89
A.gambiae AgaP_AGAP006441 1277049   XP_001688869 76
D.melanogaster Pu 37415   NP_726038 76
C.elegans cat-4 179472   NP_505710 72
S.pombe SPAC17A5.13 2542406   NP_593481 62
N.crassa NCU07774 3874842   XP_958695 61
S.cerevisiae FOL2 853183   NP_011783 59
A.thaliana AT3G07270 819915   NP_974246 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)