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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. POLR1B, polymerase (RNA) I polypeptide B, 128kDa
Sequence ID:NM_001137604
Entrez Gene ID:84172
Ensembl ID:ENSG00000125630

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 113300019 - 113335408

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6053210Full LengthBC110833polymerase (RNA) I polypeptide B, 128kDa
3833619IncompleteBC004882polymerase (RNA) I polypeptide B, 128kDa
3867133IncompleteBC073857polymerase (RNA) I polypeptide B, 128kDa
5295769IncompleteBC096748polymerase (RNA) I polypeptide B, 128kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_061887  

Protein Infomation

NM_001137604 NP_001131076      
NM_019014 NP_061887 Q9H9Y6 EC RNA_pol_Rpb2_6

Related Sequences

BC004882 AAH04882 Q9BSR4  
BC073857 AAH73857 Q6DKI9  
BC096748 AAH96748 Q4QRK8  
BC110833 AAI10834 Q2TAM4  
AK001678 BAA91831 Q9NVC2  
AK022533 BAB14082 Q9H9Y6 EC
AK022890 BAB14296 Q9H9Y6 EC
AK025574 BAB15175 Q9H6S8  
AK128044 BAC87247 Q9H9Y6 EC
AK294027 BAH11652 B7Z1W6  
AK301178 BAH13423 B7Z6Y7  
AK302814 BAH13809 B7Z823  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens POLR1B NP_061887 R.norvegicus Polr1b 83582   NP_113961 91
M.musculus Polr1b 20017 Gene Info NP_033112 90
S.pombe rpa2 2541280   NP_595819 50
N.crassa NCU08616 3880984   XP_964824 48
A.gambiae AgaP_AGAP009539 1271371   XP_310152 47
C.elegans F14B4.3 172752   NP_492476 47
S.cerevisiae RPA135 856119   NP_015335 47
D.melanogaster RpI135 33210   NP_476708 47
A.thaliana NRPA2 839872   NP_564341 45

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta