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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MYLK2, myosin light chain kinase 2
Sequence ID:NM_033118
RefSeqGene ID:NG_012847
Entrez Gene ID:85366
Ensembl ID:ENSG00000101306

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CARDIOMYOPATHY, FAMILIAL HYPERTROPHICACTC1
CAV3
MYH6
MYH7
SLC25A4
TNNC1

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q13.31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 30407383 - 30421600

 Exon Info From UCSC:
NM_033118

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262446Full LengthBC069627myosin light chain kinase 2
30530456Full LengthBC092413myosin light chain kinase 2
40085085Full LengthBC127622myosin light chain kinase 2
4110141IncompleteBC007753myosin light chain kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_149109  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_033118 NP_149109 Q9H1R3 EC 2.7.11.18 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC007753 AAH07753 Q9H1R3 EC 2.7.11.18
BC069627 AAH69627 Q9H1R3 EC 2.7.11.18
BC092413 AAH92413 Q9H1R3 EC 2.7.11.18
BC127622 AAI27623 Q9H1R3 EC 2.7.11.18
AF325549 AAK15494 Q9H1R3 EC 2.7.11.18
AJ272502 CAC81354 Q9H1R3 EC 2.7.11.18

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MYLK2 NP_149109 M.musculus Mylk2 228785 Gene Info NP_001074513 84
R.norvegicus Mylk2 117558   NP_476557 82
A.gambiae AgaP_AGAP006746 1270312   XP_308996 50
D.melanogaster CG42347 36002   NP_610514 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)