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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NOTCH3, notch 3
Sequence ID:NM_000435
RefSeqGene ID:NG_009819
Entrez Gene ID:4854
Ensembl ID:ENSG00000074181

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CEREBRAL ARTERIOPATHY WITH SUBCORTICAL INFARCTS ANDLEUKOENCEPHALOPATHY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.2-p13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 15288721 - 15311790

 Exon Info From UCSC:
NM_000435

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000426  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000435 NP_000426 Q9UM47 EGF
Ank
Notch
NOD
EGF_CA
NODP
EGF_2

Related Sequences

 
mRNAGenPeptSwissProt
U97669 AAB91371 Q9UM47
AB209447 BAD92684 Q59FL3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NOTCH3 NP_000426 R.norvegicus Notch3 56761   NP_064472 91
M.musculus Notch3 18131 Gene Info NP_032742 91

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)