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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MMP1, matrix metallopeptidase 1 (interstitial collagenase)
Sequence ID:NM_001145938
NM_002421
RefSeqGene ID:NG_011740
Entrez Gene ID:4312
Ensembl ID:ENSG00000196611

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
COPD, RATE OF DECLINE OF LUNG FUNCTION INHMOX1
SERPINA1
EBD INVERSACOL7A1

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 102660649 - 102668889

 Exon Info From UCSC:
NM_001145938
NM_002421

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3834572Full LengthBC013875matrix metallopeptidase 1 (interstitial collagenase)
3863095IncompleteBC013118matrix metallopeptidase 1 (interstitial collagenase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002412  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001145938 NP_001139410      
NM_002421 NP_002412 P03956 EC 3.4.24.7 Hemopexin
Peptidase_M10
PG_binding_1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M13509 AAA35699 P03956 EC 3.4.24.7
M15996 AAA35700 P03956 EC 3.4.24.7
BC013118 AAH13118 Q96DZ4  
BC013875 AAH13875 P03956 EC 3.4.24.7
BT006874 AAP35520 P03956 EC 3.4.24.7
BT020147 AAV38949 Q5TZP0  
DQ399597 ABD92796 A5GZ69  
DQ890729 ABM81655    
DQ893904 ABM84830    
AK223034 BAD96754 Q53G97  
AK223035 BAD96755 Q53G96  
AK223036 BAD96756 Q53G95  
AK223056 BAD96776 Q53G75  
AK223281 BAD97001 Q53FK3  
AK297723 BAG60077 B4DN15  
AK301340 BAG62888 B4DW26  
X05231 CAA28858 P03956 EC 3.4.24.7
X54925 CAA38691 P03956 EC 3.4.24.7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MMP1 NP_002412 M.musculus Mmp1a 83995 Gene Info NP_114395 60
R.norvegicus Mmp1a 300339   NP_001128002 58

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)