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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HMBS, hydroxymethylbilane synthase
Sequence ID:NM_000190
NM_001024382
NM_001258208
NM_001258209
RefSeqGene ID:NG_008093
Entrez Gene ID:3145
Ensembl ID:ENSG00000256269

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
PORPHYRIA, ACUTE INTERMITTENT 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 118955594 - 118964256

 Exon Info From UCSC:
NM_000190
NM_001024382

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822949Full LengthBC000520hydroxymethylbilane synthase
2822949Full LengthBC019323hydroxymethylbilane synthase
4178944Full LengthBC008149hydroxymethylbilane synthase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000181  NP_001019553  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000190 NP_000181 P08397 EC 2.5.1.61 Porphobil_deam
Porphobil_deamC
NM_001024382 NP_001019553     Porphobil_deam
Porphobil_deamC
NM_001258208 NP_001245137      
NM_001258209 NP_001245138      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC000520 AAH00520 P08397 EC 2.5.1.61
BC008149 AAH08149 P08397 EC 2.5.1.61
BC019323 AAH19323 P08397 EC 2.5.1.61
HQ448217 ADQ32697    
HQ731552 ADX60069 F1DBF3  
D28419 BAA05785    
AK290275 BAF82964 P08397 EC 2.5.1.61
X04217 CAA27801 P08397 EC 2.5.1.61
X04808 CAA28499 P08397 EC 2.5.1.61

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HMBS NP_000181 M.musculus Hmbs 15288 Gene Info NP_038579 91
R.norvegicus Hmbs 25709   NP_037300 91
A.gambiae AgaP_AGAP011080 3291232   XP_564464 57
D.melanogaster l(3)02640 46140   NP_612103 55
N.crassa NCU10292 5847103   XP_001728039 45
S.pombe hem3 3361383   NP_001018179 45
S.cerevisiae HEM3 851322   NP_010076 43
A.thaliana HEMC 830724   NP_196445 40
P.falciparum PBGD 811149   XP_001350505 34

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta