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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GSS, glutathione synthetase
Sequence ID:NM_000178
RefSeqGene ID:NG_008848
Entrez Gene ID:2937
Ensembl ID:ENSG00000100983

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 33516630 - 33539655

 Exon Info From UCSC:
NM_000178

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3946317Full LengthBC007927glutathione synthetase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000169  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000178 NP_000169 P48637 EC 6.3.2.3 GSH_synthase
GSH_synth_ATP

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U34683 AAB62390 P48637 EC 6.3.2.3
BC007927 AAH07927 P48637 EC 6.3.2.3
DQ893238 ABM84164    
DQ896568 ABM87567    
AK312492 BAG35394 P48637 EC 6.3.2.3
AB459500 BAG75452 B6F210  
AK293144 BAH11461 B7Z1C5  
AK298292 BAH12750 B7Z514  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GSS NP_000169 M.musculus Gss 14854 Gene Info NP_032206 89
R.norvegicus Gss 25458   NP_037094 88
A.gambiae AgaP_AGAP000534 1271707   XP_310552 43
D.melanogaster CG32495 318053   NP_788927 43
D.melanogaster GS 32775   NP_788925 43
A.thaliana GSH2 832797   NP_568495 42
N.crassa NCU06191 3879151   XP_963003 41
C.elegans M176.2 174493   NP_496011 40
S.pombe gsa1 2542896   NP_593936 39
S.cerevisiae GSH2 854108   NP_014593 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta